Formulating, Manufacturing and Stability
Some of the probiotic strains used in Alcrea house formulas have been studied in vitro and found to be acid-resistant and survive bile acids of the duodenum. This reduces the need to use enteric-coated capsules for probiotic supplements, as has been the standard in the past. Clinical analysis shows increased binding to the human intestinal wall and protective effects of intestinal colonization. Alcrea handles and manufactures probiotic products using strict temperature and humidity controlled environments.
More on Probiotics
Probiotics are ‘friendly bacteria’ that promote intestinal balance. Research is increasing quickly, and the market is growing right along with the results. While it is still considered to be in its infancy, probiotics are at the top of the list, along with omega-3s, for top selling supplements in the market.
Probiotic dietary lactobacilli colonize the intestinal tract. Bacteria are continually in competition for space, the original bacterial colonies having an advantage over transient bacteria. However, the composition of the intestinal microflora is dynamic and constantly changing. If harmful microorganisms proliferate, the equilibrium is disturbed, and it becomes difficult even for indigenous bacteria to maintain their territory in the intestine.
Antibiotics tend to kill off both beneficial and harmful bacteria, which may also disturb the normal, healthy balance of intestinal microorganisms. Various intestinal conditions can compromise the immune system and lower the amounts of healthy intestinal microflora. When potent probiotics are supplied regularly, chances are greatly increased for establishing and maintaining a healthy population of beneficial intestinal microorganisms. Once established, a normal intestinal microflora rich in lactobacilli creates acidic conditions that are unfavorable for the settlement of pathogenic microorganisms.
Don’t forget about prebiotics
Since 2009, the benefits of prebiotics have been more widely acknowledged as a necessary component for gut health. Prebiotics are carbohydrates that have short molecular chains. They function as non-digestible ingredients that can positively affect selected groups of beneficial intestinal microflora, such as lactobacillus. While probiotics merely add beneficial microflora, prebiotics affect the intestinal environment so that beneficial colonies of microflora can flourish. By aiding the beneficial microflora’s survival, pathogenic microflora can have a decreased chance of survival.
Additional Probiotic Research
L. gasseri strain supplementation has shown a beneficial effect on immunological reactions in school children.
Lactobacillus rhamnosus is one of the most widely studied probiotics, noted and valued for its ability to survive in the harsh conditions of the digestive and urinary tracts. L. rhamnosus is extremely well tolerated by men and women with very few side effects. Studies have shown that, taken regularly, L.rhamnosus can be an effective supplement in promoting and maintaining digestive tract health.
The ability for probiotic cultures to survive stomach acidity and pH has been in question. Bifidobacterium was studied in vitro to be extremely resistant to low pH and bile acids in the duodenum.
L. acidophilus DDS-1™ incorporates proprietary cryoprotectant agents and stabilizers specifically designed to protect the organism and enhance stability. Clinical analysis of DDS-1 and Bifidobacterium also shows increased binding to human intestinal walls and protective effects of intestinal colonization. Certain bacterial acids in the intestines produce secondary bile acids, which have been implicated as promoters of colon carcinogenesis. One study indicated that L. acidophilus DDS-1 decreased the potential for bacterial transformations of primary bile acid.
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This product is not intended to diagnose, treat,
cure or prevent any disease.